However, being highly amplified in a small proportion of patients bearing lung adenocarcinoma (LUAD), bladder urothelial carcinoma (BLCA), breast invasive carcinoma (BRCA) and lung squamous cell carcinoma (LUSC), the expression of ITGA10 is conversely decreased in these tumors at population level (Fig. 2d), suggesting other mechanisms involved in its transcriptional regulation. This evidence concerns the gene ITGA10 and invasive breast carcinoma.