Finally, the plasma levels of sCD62P and sCD40L of COVID-19 patients were significantly higher than those observed in the plasma samples of convalescent patients (22,886 and 290 pg/ml, for sCD62P and sCD40L respectively), regardless of sampling time, except for the sCD62P level assessed in the first time point, which did not differ significantly from those in convalescent patients. The gene discussed is CD40LG; the disease is COVID-19.