Analyzed from GEO database, we further found that the enhanced PLA2G16 was in breast cancer tissues with a partial response (pPR) to neoadjuvant paclitaxel/radiation treatment in contrast to these with pathologic complete response (pCR) to neoadjuvant treatment, suggesting that PLA2G16 was closely related to poor prognosis and chemo-resistance in breast cancer patients (Fig. 4H). The gene discussed is PLAAT3; the disease is breast cancer.