PLAAT3 and non-small cell lung carcinoma: On the contrary, Irina Nazarenko and his colleagues found that PLA2G16 is not only inducing cells proliferation, driving poor prognosis of patients in non-small cell lung cancer, but also up-regulation in stomach, colon, and rectum cancers, illustrating that PLA2G16 serves as an oncogenic role in these tumors [21].