SUMO2 and glioblastoma: SUMO2/3 high expression was also found to be predominantly associated with both chemo and radioresistant GBM samples, as per the analysis of microarray data submitted by Murat et al. [GSE7696] [40] (Fig. 2D and Additional file 4: Table S26), but amongst the two isoforms only SUMO2 was found to be significantly associated with the GBM patient reduced survival (Fig. 2E and Additional file 4: Table S27).