Recent literature by Zhou et al. indicates that severe coronavirus disease 2019 (COVID-19) accompanies by an aggressive inflammatory response known as a cytokine storm [2], that bears similarities to sHLH (including excess production of tumor necrosis factor-α (TNF- α), monocyte chemoattractant protein-1 (MCP1), and interleukin-2 [IL-2]). Here, TNF is linked to COVID-19.