EPCAM and neoplasm: The Catuvab procedure consists of Catumaxomab crosslinking EpCAM positive tumor cells with CD3 positive T-cells and Fc-gamma receptor positive immune cells, removal of these cell aggregates during a centrifugation step from EC and final removal of residual tumor cell containing cell aggregates during a final filtration step using a 40 μm leukocyte depletion filter (LDF).