HPSE2 and psoriasis: It was observed higher protein expression of HPSE2 in the Psoriasis group concerning the Non-affected group 157.06 ± 11.19 ou/μm2 versus 117.75 ± 7.49 ou/μm2 (p < 0.0001) and Psoriasis group compared to Control 157.06 ± 11.19 ou/μm2 versus 104.08 ± 9.24 ou/μm2 (p < 0.0001), demonstrated in Fig. 3.