KRAS and neoplasm: Among Kras tumor-bearing wildtype mice, quantifying tumor-associated FOXP3+ cells in lung sections revealed a >3-fold induction of FOXP3+ cell density compared to that noted in the non-tumor background/interstitial lung tissue [compare mean FOXP3+ cell density in wildtype mice in Fig. 2A (∼ 9/HPF) to that noted in Fig. 2B (∼ 30/HPF)].