CD8A and neoplasm: We derived and pooled single-cell suspensions of tumor-infiltrating lymphocytes from six spatially distinct regions of the nephrectomy specimens from ADR013 (responder) and ADR001 (non-responder) sorted nivolumab-bound CD8+ T cells and analyzed them via high-dimensional flow cytometry and single-cell RNA (scRNA-seq) and single-cell TCR (scTCR-seq) sequencing (STAR Methods).