The top differentially expressed genes (unadjusted P ≤ .001) were all upregulated and included KIFC1 (OMIM 603763), FAM83D (OMIM 618380), UBE2C (OMIM 605574), CLDN4 (OMIM 602909), GRB7 (OMIM 601522), and PKMYT1 (OMIM 602474), each of which have previously reported roles in breast cancer progression. The gene discussed is PKMYT1; the disease is breast cancer.