MAPK1 and nodular sclerosis classical Hodgkin lymphoma: By using the ingenuity pathway analysis (IPA) software, from which TGFB1 (with 35 connections) was found in the central node of the network in the first group (NSHL group of genes) and MAPK3/MAPK1 MAP kinase (with 33 gene connections) was identified as the central node of the network in the second group (both syndromic and NSHL group of genes) [23].