In case of ion transport (group II), both UBC and RAC1 have the co-expression with ACTB gene; whereas CDH23 built a co-expression with OTOF and ATP2B2. Lastly in sensory signaling category (group IV), the co-expressions found between CDH23 and three other genes, i.e. OTOF, MYO7A, and ATP2B2; whereas MYO7A has built only one co-expression with CDH23. These co-expressed genes of respective biological process groups might be considered as putative genes for NSHL (Table 2). The gene discussed is RAC1; the disease is nodular sclerosis classical Hodgkin lymphoma.