FGFR2 and LADD syndrome: However, the variants of FGFR1 and FGFR2 have been found in hypogonadotropic hypogonadism 2 with anosmia (rs121909642) [49], Pfeiffer syndrome [50], craniosynostosis syndrome [51] (rs121918506), and in LADD syndrome (rs121918509) [52,53], respectively.