Previous studies have reported that linc00467 promotes cell proliferation and metastasis through insulin-like growth factor-2 messenger RNA-binding protein 3/tumor necrosis factor receptor-associated factor 5, miR-18a-5p/neural precursor cell expressed developmentally down-regulated 9, miR-509-3p/platelet-derived growth factor receptor alpha pathways, indicating linc00467 signaling may impede apoptosis, and contribution to axitinib resistance of HCC, these results indicated that linc00467 may serve as a promising biomarker and target for HCC treatment [23,25,26]. The gene discussed is IGF2; the disease is hepatocellular carcinoma.