TIMP2 and acute kidney injury: To substantiate our data on the involvement of TxT‐sEVs in distant organ damage, we interrogated published AKI‐relevant transcripts.[57] Kim1 was significantly upregulated by TxT‐sEVs after 4 h, whereas Lcn2 (NGAL) and Timp2 were upregulated 16 h after administration (Figure 8e).