GATA2 and acute myeloid leukemia: GATA2 is one of the master regulators of blood production and patients that carry a mutation in one of the two alleles of GATA2 often manifest with immunodeficiency syndromes and increased lifetime risk for MDS/AML (Wlodarski et al., 2016; Donadieu et al., 2018; McReynolds et al., 2018).