These probiotics have been reported to have good therapeutic potential in treating diarrhea, inflammatory bowel disease, and acute pancreatitis [6,7,8], and the primary mechanism might be through the modulation of the nuclear factor-kappa B (NF-κB) signaling pathway mediated by toll-like receptor 4 (TLR4) [9]. Here, TLR4 is linked to acute pancreatitis.