Moreover, inhibition of TRIM8 by downregulation of long noncoding RNA (lncRNA) LINC00472, which served as a sponge for miR-373-3p and negatively regulated its expression, could reduce sepsis-induced expression of main proinflammatory cytokines such as IL-6, IL-10, and TNF-α [51]. Here, TRIM8 is linked to Sepsis.