Most recently, Whitson et al. had evaluated the therapeutic benefits of recombinant human TRIM72 protein in porcine models of ALI and found that recombinant TRIM72 protein can mitigate lung injury in the porcine model of combined hemorrhagic shock/contusive lung injury and reduce warm ischemia-induced injury to the isolated porcine lung through ex vivo lung perfusion administration [46]. This evidence concerns the gene TRIM72 and acute respiratory distress syndrome.