The overexpression of KIF14 may lead to rapid and error-prone mitosis [39] and is involved in the progression of a variety of malignancies, such as retinoblastoma and gastric cancer [40, 41], providing evidence that KIF14 may be an oncogene in the progression of a variety of cancers, while in the study of lung adenocarcinoma, it was found that KIF14 was underexpressed in 30% of cancer tissue samples [42], and the decreased expression of KIF14 was significantly correlated with the overall survival rate of lung cancer patients [43]. This evidence concerns the gene KIF14 and retinoblastoma.