The result indicated that the expression trends of partial HSPs were consistent at mRNA level and protein level in 5 types of cancer, such as TRAP1, HSPD1 and HSPA12B in lung cancer; HSPA6, HSPA12A, HSPA4L and HSPA12B in breast cancer; HSPA1L in endometrial cancer; HSPA2 and HSPA1A in colorectal cancer; HSPA12A, HSPA12B and HSPA2 in renal carcinoma (Table 2). The gene discussed is HSPA12B; the disease is colorectal cancer.