Generally, tumor-derived TGF-β can attract myeloid and lymphoid cells, but it also leads to immunosuppression and immune evasion of tumors by changing proliferation and differentiation of residential T cells, neutrophils and macrophages, dendritic cells and NK cells (Batlle and Massagué, 2019; Brown and Marshall, 2019). This evidence concerns the gene TGFB1 and neoplasm.