To check the effect of miR-146a on in-vivo tumor formation, SCC084 cells harboring either an empty vector (SCC084/EV) or stably expressing miR-146a (SCC084/miR-146a), were generated and the over-expression of miR-146a with subsequent downregulation of CD24 was confirmed by both qRT-PCR and western blotting (Figures S6A–C). The gene discussed is CD24; the disease is neoplasm.