As a result, for TCGA-derived high-risk patients, GSEA pathways were associated with angiogenesis, apoptosis, PI3K-AKT-MTOR signal pathway, epithelial-mesenchymal transition, and glioma stem cell pathway (Figure 5(a)), which were verified using the CGGA database (Figure 5(b)). The gene discussed is AKT1; the disease is central nervous system cancer.