ADAMTS2 and Ehlers-Danlos syndrome, dermatosparaxis type: While TEM analysis of the skin of 2-day-old Adamts2–/– mice was unremarkable, 2-month-old Adamts2–/– mice showed collagen fibrils with an unusually curled morphology, a finding consistent with the “hieroglyphic” appearance of cross-sectional collagen fibrils in human dEDS patients (Colige et al., 2004).