B3GALT6 and skeletal dysplasia: b3galt6–/– zebrafish showed progressive skeletal malformations with variable severity, including reduced body length, misshapen cranial bones, smaller teeth, and general skeletal dysplasia with kyphosis and scoliosis (Figure 6C), which are reminiscent of the skeletal dysplasia phenotype observed in spEDS-B3GALT6 patients.