ADAMTS2 and Ehlers-Danlos syndrome, dermatosparaxis type: Around the age of two months, Adamts2–/– mice developed triangular facies with a shorter snout, had less dense hair with thinner hair follicles, but lacked craniofacial abnormalities or growth retardation, unlike dEDS patients (Li et al., 2001; Goff et al., 2006).