Skin hyperextensibility Easy bruising Rupture/aneurysm of medium-sized artery Osteopenia/osteoporosis Blue sclerae Umbilical or inguinal hernia Pectus deformity Marfanoid habitus Talipes equinovarus Refractive errors kEDS-PLOD1: Skin fragility Microcornea Characteristics craniofacial features kEDS-FKBP14: Congenital hearing impairment Muscle atrophy Bladder diverticula. The gene discussed is PLOD1; the disease is Osteopenia.