CAMKK2 and neoplasm: To evaluate whether the failure to expand MDSCs has an important causative role in the mechanism of tumor suppression, Gr1+ MDSC, which include both subsets of M-MDSC and G-MDSC cells were isolated from the spleens of E.G7-OVA-bearing WT and Camkk2-/- then adoptively transferred into Camkk2-/- mice via tail vein injection.