Based on TCGA and CGGA datasets, analysis of pan-glioma cohorts revealed that patients with higher expression of TNFSF13 exhibited dramatically poorer overall survival (OS) than patients with lower expression of TNFSF13, and similar correlations were noticed in LGG and GBM cohorts (Supplementary Figures S4A, B). This evidence concerns the gene TNFSF13 and central nervous system cancer.