IL10 and colitis: Previous studies have shown that the absence of L. reuteri leads to colic in infants, L. reuteri supplementation alleviates the damage of DSS-induced colitis in mice, and L. reuteri can be used to treat enteritis in IL-10-deficient mice (Madsen et al., 1999; Liu et al., 2012; Bene et al., 2017; Mu et al., 2017, 2018; Savino et al., 2018).