Select markers were evaluated in lesions of CD-fed and HFD-fed recipients, based on their strong association with the inflammatory process (Il-6, Il-8, and Cox2; Lai et al., 2019); their previous identification as induced by HFD in Klf9-null lesions (Il-17α and Cxcl4; Heard et al., 2016) and the known macrophage participation in endometriosis-associated inflammation (CxCl2; Hogg et al., 2021). The gene discussed is IL6; the disease is endometriosis.