Compared with normal tissues, ABCA1, APLNR, BTG2, C3AR1, CALCRL, CD14, CYBB, HIF1A, MMP14, MYC, SELL, and SLC4A4 were upregulated in LGG tumor tissues, and SCN1B was downregulated in tumor tissues (Figure 1A). The gene discussed is CALCRL; the disease is neoplasm.