NR3C2 and hydrops fetalis: Specifically, >99% of participants in PRESERVED-HF were receiving diuretics (versus 86 and 96% in EMPEROR-PRESERVED and PARAGON-HF, respectively) and 36% of participants in PRESERVED-HF were receiving mineralocorticoid receptor antagonists, a rate that was greater than in PARAGON-HF (24%) and similar to that in EMPEROR-PRESERVED (37%)15,19,20.