MEN1 and pachyonychia congenita: Furthermore, western blot (WB) analysis in PC models showed that Menin expression was 4-fold higher in CRPC (LNCaP-HSP27) compared to CSPC (LNCaP-Mock) model (Figs. 1A and S1A) and 2-fold higher in AI PC-3 and DU-145 cell lines than in CSPC LNCaP cell lines (Figs. 1B and S1B).