MEN1 and pachyonychia congenita: Genomic Regions Enrichment of Annotations Tool (GREAT) determination of the corresponding genomic regions gene demonstrated twice more Menin target genes at TSS genes in cancer LNCaP (11127) and PC-3 (10113) compared to normal PNT1A (6417) cells, suggesting distinct roles of Menin during PC progression (Fig. 5A).