EYA1 and cancer: Because it is the most highly regulated pathway, we focused our attention on the “transcriptional misregulation in cancer pathway” (hsa05202), containing three identified proteins (DEAD-Box Helicase 5, DDX5; eyes absent 1 protein, EYA1, and Menin) present in CRPC model (LNCaP-HSP27) and not detected in CSPC model (LNCaP-Mock) (not shown).