MYD88 and Sepsis: Preterm neonates have lower expression of TLR 4 and MyD88 on monocytes, and reduced response to LPS and lipoteichoic acid in vitro, which may contribute to the high rate of severe bacterial infections and sepsis in this cohort.50 There is a paucity of data on similar expression in other myeloid cell lineages including preterm and neonatal platelets.