Production of IFN-γ was also exacerbated in tumor infiltrating in both CD4Pos T cells and CD8pos T cells from Foxp3ΔItgβ8 mice compared to Foxp3Ctrl animals (Supplementary Fig. 2), implying that in addition of GzB production and the cytotoxic granule release, the exacerbated production of IFN-γ by T cells could also contribute to the tumor growth control in Foxp3△Itgβ8 mice. Here, IFNG is linked to neoplasm.