NGEF and laryngotracheoesophageal cleft: When compared to the corresponding normal tissues, the levels of Ephexin1 in CRC (n = 639) and LC (n = 994) were more than 26-fold higher than that of normal sample tissues (Fig. 1A) and increased Ephexin1 expression in CRC and LC tissues correlated with poor overall survival (Fig. 1B).