However, baseline IL-6 could discriminate tuberculosis patients with and without unfavorable treatment outcomes with an AUC of 0.71 (95%CI 0.65-0.77); a z-score cut-off of -0.32 identified by the Youden’s method had a sensitivity of 76%, specificity of 60%, and a negative predictive value of 85% for ruling out subsequent unfavorable tuberculosis treatment outcomes. This evidence concerns the gene IL6 and tuberculosis.