Our results revealed that CPN1 upregulation was a negative independent predictor for OS (HR = 3.275, 95% CI 2.201–4.873; P < 0.05) and PFS (HR = 2.309, 95% CI 1.164–4.580; P < 0.05) in patients with IBC. This evidence concerns the gene CPN1 and inflammatory breast carcinoma.