As shown in Fig. 3C, this LDHA KD not only resulted in IPF AEC2 with an LDH tetramer expression pattern more closely resembling that of representative AEC2s from non-fibrotic lungs (compare Fig. 2B), but also significantly increased IPF AEC2 OCR to levels similar to those non-fibrotic AEC2 (compare Fig. 1A). Here, LDHA is linked to idiopathic pulmonary fibrosis.