The cancer cluster region for BRCA2 in ovarian cancer is located from c.3249 to c.5681 (RHR = 0.51; 95% CI, 0.44–0.60; P = 6 × 10− 17) and c.6645 to c.7471 (; RHR = 0.57; 95% CI, 0.41–0.80; P = .001) [58]. This evidence concerns the gene BRCA2 and cancer.