To investigate the fundamental role played by the CXC chemokines, including CXCL1, CXCL10 and CXCL12 in AML patients prior and post BMT, the present study was carried out on 46 AML patients (23 AML-M1 and 23 AML-M3). This evidence concerns the gene CXCL10 and acute myeloid leukemia.