To investigate the fundamental role played by the CXC chemokines, including CXCL1, CXCL10 and CXCL12 in AML patients prior and post BMT, the present study was carried out on 46 AML patients (23 AML-M1 and 23 AML-M3). The gene discussed is CXCL12; the disease is acute myeloid leukemia.