Moreover, in concordance with other studies, our work revealed that HBME-1 (Saleh et al., 2010; Palo and Biligi, 2017; Zargari and Mokhtari, 2019) and Galectin-3 (Saleh et al., 2010; Muzafar et al., 2017) had the highest sensitivity for the diagnosis of thyroid carcinoma. This evidence concerns the gene LGALS3 and thyroid gland carcinoma.