TGFB1 and hepatocellular carcinoma: Many variants of TGF-β1 including +869 C>T and –509 C>T were previously demonstrated to be associated with susceptibility to HCC (Guo et al., 2013; Lu et al., 2016; Toshikuni et al., 2016), however the present work is considered the first to identify Arg25Pro variant to be related to HCC risk in Egyptian population.