Another study on p16INK4A expression in 24 CA specimens showed that overexpression of p16INK4A were sporadic in 11/24 of the specimens (45.8%), were focal in 7/24 of the specimens (29.2%), and were negative in 6/24 of the specimens (25%) (Kazlouskaya et al., 2013). This evidence concerns the gene CDKN2A and cancer.