Present investigation strongly suggests that (NSFC) complex compound, additionally to its high potential antitumor activity in-vitro, has also a radical scavenging effect in-vivo by encountering free radicals after tumor cells inoculation which revealed marked amelioration within the depleted GSH content and scavenger enzymes, (GSH Px and SOD) activities within the blood of tumor-bearing mice, treated by novel complex drug (NSFC) with or without radiation exposure (IR). Here, SOD1 is linked to neoplasm.