For example, genes encoding the albumin receptors cubilin (CUBN) and the neonatal Fc receptor (FCRN) were up-regulated in the presence of albumin, independently of infection, while SPARC, coding for an albumin binding protein, was up-regulated only during infection at 24 h, but not in uninfected control conditions (24 c) (Fig 2g). Here, ALB is linked to infection.