ASB16 and osteosarcoma: For example, ASB16-AS1 promoted the proliferation and invasion of gastric cancer by regulating the expression level of TRIM37 [10]; Up-regulation of ASB16-AS1 expression promoted the proliferation and inhibited apoptosis in non-small cell lung cancer by Wnt signaling pathway [11]; ASB16-AS1 regulated the up-regulation of HDGF expression to promote the malignant phenotype of osteosarcoma by sponging miR-760 [12].