Since the differences seen between survivors and non-survivors may not be proposed as mortality risk factors per se, additional multivariate logistic regression analysis included the following variables: age, male gender, in-hospital stay, AKIN stage 2, minimal EGFR, peak CRP, NT-proBNP, ICU treatment for longer than 10 days, insulin-dependent diabetes, the absence of CKD or CHF, BMI, and a negative history neoplasia. This evidence concerns the gene NPPB and chronic kidney disease.