APOB and familial hypercholesterolemia: trials Arterioscler Thromb Vasc Biol Arterioscler Thromb Vasc Biol 2015 2015 35 35 3 3 689 689 699 699 25614280 25614280 Santos RD, Raal FJ, Catapano AL et al. Mipomersen, an antisense oligonucleotide to apolipoprotein B-100, reduces lipoprotein(a) in various populations with hypercholesterolemia: results of 4 phase III.