CD4 and neoplasm: Assessing cell types in the tumor, we saw more CD8+ and CD4+ T cell infiltration (Figure 3K–L), along with higher IFN-γ production from both CD4+ (Figure 3M) and CD8+ (Figure 3N) T cells in Pgdfl/flFoxp3EGFP-Cre-ERT2 versus WT mice.