Hence, PET imaging targeting c-MET expression using 68Ga-EMP-100 might allow a pretherapeutic estimation of treatment efficacy by non-invasive evaluation of all tumor lesions beyond the possibility of assessing the c-MET expression from a single tumor sample such as tumor resection or biopsy with the respective sampling errors in heterogeneous tumors [31]. The gene discussed is MET; the disease is neoplasm.