S100A8 and autoimmune thrombocytopenic purpura: Various mechanisms of H-pylori induced ITP have been proposed by various researches in literature; however, the most commonly discussed mechanism is the role of molecular mimicry (production of autoantibodies against H-pylori virulent factor CagA and cross reactivity of these antibodies with various surface antigens such as GP IIb/IIIa, GP Ib/IX, and GP Ia/IIa, on platelet membranes).