On a sample of 243 lung adenocarcinomas and using Hercep Test Dako, Yoshizawa et al. detected HER2 overexpression in 37 patients (score 2+ and 3+), among whom HER2 gene amplification was found in four patients using “Dual ISH, Ventana Medical Systems” [20]. Here, ERBB2 is linked to lung adenocarcinoma.