In a previous study in rats with induced myocardial infarction (30), peroxisome proliferator-activated receptor γ (PPAR-γ) was verified to be the target of miR-130b, and expression of miR-130b was associated with NFκB-mediated cardiac inflammation and TGF-β1-mediated cardiac fibrosis. This evidence concerns the gene TGFB1 and inflammatory response.